neuroConstruct projects based on published neuronal and network models
- DentateGyrus
- GranCellLayer
- GranuleCell
- MainenEtAl_PyramidalCell
- PurkinjeCell
- RothmanEtAl_KoleEtAl_PyrCell
Downloadable neuroConstruct projects based on published conductance based models. Some examples to illustrate the core functionality of neuroConstruct, as opposed to providing electrophysiologically accurate models can be found here
DentateGyrus
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Project name: DentateGyrus A recreation of the model Dentate Gyrus from: Santhakumar V, Aradi I, Soltesz I. Role of mossy fiber sprouting and mossy cell loss in hyperexcitability: a network model of the dentate gyrus incorporating cell types and axonal topography. J Neurophysiol. 2005. Based on model scripts obtained from: http://senselab.med.yale.edu/senselab/modeldb/ShowModel.asp?model=51781 Project last modified: Monday June 15, 2009 |
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GranCellLayer
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Project name: GranCellLayer An extension in 3D of the Granule Cell Layer model from: Maex, R and De Schutter, E. Synchronization of Golgi and Granule Cell Firing in a Detailed Network Model of the Cerebellar Granule Cell Layer J Neurophysiol, Nov 1998; 80: 2521 - 2537. The default Simulation Configuration replicates the 1D 75 granule cell example from: http://www.tnb.ua.ac.be/models/network.shtml Project last modified: Wednesday October 14, 2009 |
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GranuleCell
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Project name: GranuleCell A project illustrating the behaviour of the Granule Cell model from: Maex, R and De Schutter, E. Synchronization of Golgi and Granule Cell Firing in a Detailed Network Model of the Cerebellar Granule Cell Layer J Neurophysiol, Nov 1998; 80: 2521 - 2537. Based on scripts obtained from: http://www.tnb.ua.ac.be/models/network.shtml. This project shows how a cell model with multiple active conductances can produce the same behaviour on NEURON and GENESIS through the specification of channel mechanisms in ChannelML. Project last modified: Wednesday October 14, 2009 |
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MainenEtAl_PyramidalCell
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Project name: MainenEtAl_PyramidalCell Implementation of the Mainen et al. pyramidal cell model from: Mainen ZF, Joerges J, Huguenard JR, Sejnowski TJ (1995) A model of spike initiation in neocortical pyramidal neurons. Neuron 15:1427-39. This project is based on scripts obtained from: http://senselab.med.yale.edu/senselab/modeldb/ShowModel.asp?model=8210 Project last modified: Tuesday February 24, 2009 |
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PurkinjeCell
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Project name: PurkinjeCell An initial implementation in NeuroML of the Purkinje Cell model from De Schutter, E. and Bower, J. M. (1994). Based on Arnd Roth el al's conversion of the original GENESIS code to NEURON. Project last modified: Wednesday July 15, 2009 |
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RothmanEtAl_KoleEtAl_PyrCell
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Project name: RothmanEtAl_KoleEtAl_PyrCell Status: needs further testing of mappings to GENESIS and PSICS!! Project last modified: Tuesday February 24, 2009 |
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* Note: neuroConstruct project downloads (most of which are included with the standard software distribution) can be loaded directly into neuroConstruct to generate cell and network scripts for NEURON, GENESIS, etc., but NeuroML downloads just consist of the core elements of the project (morphologies, channels, etc.) which have been exported in NeuroML format. The latter can be useful for testing NeuroML compliant applications. If no NeuroML download link is present, this usually indicates that the model is mainly implemented using channel/synapse mechanisms in a simulator's native language (e.g. mod files) which have not fully been converted to ChannelML yet.